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يستعمل دواء ميرينا 20مكجم/24 ساعة mirena intrauterine delivery system 20mcg/24 hrs contraception contraception
20 microgram / 24 hours - -a synthetic progestagen . hormonal contraception. - -mechanism of action of levonorgestrel -it is a progestin derivative exerts it`s action through nuclear progesterone receptors situated in female genital tract breast cns and pituitary. when the drug binds to progesterone receptors it undergoes dimerisation and attaches to progesterone response element of target genes and regulates transcription through coactivators. it inhibits growth hormone release from pituitary by reinforcement of normal feedback inhibition. it reduces frequency of lh secretary pulses attenuate lh surge and suppresses ovulation. it causes thickening of cervical mucous and induces sloughing of the endometrium. it also disrupts fertilization and inhibits implantation. -indications for levonorgestrel -1. emergency contraception -2. long term prevention of pregnancy (up to 5years)
تركيبة دواءميرينا 20مكجم/24 ساعة mirena intrauterine delivery system 20mcg/24 hrs
يتركب هذا الدواء من :levonorgestrel
الشركة المنتجة لدواءميرينا 20مكجم/24 ساعة mirena intrauterine delivery system 20mcg/24 hrs
هذا الدواء من انتاج شركة bayer schering > bayer healthcare
جرعة دواءميرينا 20مكجم/24 ساعة
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