يستعمل دواء دوسبا 40 مجم/ 2 مل 5 امبولاتdo-spa 40mg/2ml 5 amp. antispasmodic antispasmodic

about drotaverine -drotaverine is an effective spasmolytic drug. - -mechanism of action of drotaverine -drotaverine has spasmolytic and vasodilating action. it exerts its action by inhibiting phosphodiesterase enzyme iv. this will leads to a decrease in cyclic amp level and reduction in calcium ions (ca2+). the reduction of calcium ions will dilates the unstipped muscles and blood vessels strongly and relieves spasm of smooth muscles. - -indications for drotaverine -1.smooth muscle spasm -2.gastrointestinal colic pain -3.renal colic pain -4.dysmenorrhoea -5.uterine neck spasm -6.post mtp(medical termination of pregnancy) -7.post d&c(dilatation and curettage) -8.post surgical spasm -9.irritable bowel syndrome