يستعمل دواء تونادوجيست 10مجم 30 اقراصtonadogest 10 mg 30 f.c. tabs. progestogens progestogens

about dydrogesterone -it is in the class of progestogens. - -mechanism of action of dydrogesterone -it is a progestin derivative exerts it`s action through nuclear progesterone receptors situated in female genital tract breast cns and pituitary. when the drug binds to progesterone receptors it undergoes dimerization and attaches to progesterone response element of target genes and regulates transcription through coactivators; which ultimately leads to modification of protein synthesis. it contributes to proper development and maintenance of female sexual functions. it prepare uterus for nidation and maintenance of pregnancy. it prevents endometrial shedding decreases uterine motility and also inhibits immunological rejection of the foetus by decreasing t-cell function and cell mediated immunity.