يستعمل دواء فوتريسين بي 50مجم امبولphotericin b 50 mg vial antifungal.polyene antifungal.polyene

about amphotericin-b -it is a polyene antifungal antibiotic. - -indications for amphotericin-b -1.oral cutaneous vaginal candidiasis -2.otomycosis -3.mucocutaneous candidiasis -4.fungal meningitis -5.kala azar -6.cryptococcosis -7.histoplasmosis -8.coccidioidomycosis -9.blastomycosis -10.paracoccidioidomycosis -11.aspergillosis -12.sporotrichosis -13.systemic mycoses - -mechanism of action of amphotericin-b -amphotericin b has high affinity for ergosterol present in the fungal cell membrane and bind with it and they orients in such a way that micropore channel are formed and leads to efflux of ions amino acid sugar and other water soluble substances and results in cell disruption. - -